# Macule, Papule, Nodule, Plaque, Wheal, Vesicle,…! What!?

Like any other field of knowledge, Medicine includes many jargons that may seem redundant! They are not! Some of the examples are the following terms: Macule, Papule, Nodule, Plaque, Wheal, Vesicle, Blister, Pustule, Abcsess, Cyst, Atrophy! But what are they exactly!? Can you distinguish!?

۱٫ Macule

Macules are circumscribed alterations in skin color. The skin surface is neither elevated or depressed in relation to the surrounding skin. Macules may be of any size or color.

Macule 1 Macule 2


۲٫ Papule

Papule is a solid, elevated lesion with no visible fluid which may be up to ½ cm. in diameter.

Papule 1 Papule 2 Papule 3

۳٫ Nodule

Nodules are forms of papules, but are larger and deeper. They may be located in the dermis or subcutaneous tissue, or in the epidermis. Nodules are usually ½ cm. or more in diameter.

Nodule 1 Nodule 2 Nodule 3

۴٫ Plaque

 An elevated area of skin 2 cm. or more in diameter. It may be formed by a coalescence of papules or nodules. The surface area is greater than its height. It is a plate-like lesion.

Plaque 1 Plaque 2

۵٫ Wheal

A wheal is an evanescent rounded or flat-topped elevation in the skin that is edematous, and often erythematous. They may vary in size from a few mm. to many cm. The shape may change and these lesions are usually pruritic (itchy).

Wheal 1 mh_fitz_fig14-5.tif

۶٫ Vesicle

Vesicles are circumscribed epidermal elevations in the skin containing clear fluid and less than ½ cm. in diameter. If the lesion has a diameter of greater than ½ cm, it is called a bulla. Vesicles and bullae are commonly called blisters.

Vesicle 1 Vesicle 2

Also Notice: Vesicles vs. Bullae

Vesicles vs. Bullae۷٫ Pustule

A pustule is a circumscribed elevation of the skin that contains a purulent exudate that may be white, yellow, or greenish-yellow in color.

Pustule 3 Pustule 2

۸٫ Abcess

A localized collection of pus in a cavity formed by disintegration or necrosis of tissue.

Abscess 2 Abcsess 1

and 9. Cyst

A cyst is a closed sac that contains liquid or semisolid material. On palpation a cyst is usually resilient.

Cyst 2 Cyst 1

Now, you can easily differentiate among these terms!   😀

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